反応 #64972

反応方程式

7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

NaOH

K2CO3

→

1,2-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

溶媒

water

反応条件

後処理

1. 1
   抽出extracted several times with CHCl3
2. 2
   乾燥the extract is dried over K2CO3
3. 3
   濃縮concentrated
4. 4
   workup.DISTILLATIONthe residue is distilled

実験手順

11.8 g (64mmol) of 7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane are heated under reflux with 12 g of NaOH in 36 ml of water overnight. The mixture is saturated with K2CO3 and extracted several times with CHCl3, the extract is dried over K2CO3 and concentrated and the residue is distilled.

出典