反応 #64962

反応方程式

allyl chloride

N-(1,1-dimethoxyprop-2-yl)urethane

sodium hydride

hydrogen

→

N-Allyl-N-(1,1-dimethoxyprop-2-yl)-urethane

溶媒

toluene

反応条件

後処理

1. 1
   その他The sodium chloride which has precipitated out
2. 2
   workup.DISSOLUTIONis dissolved with water
3. 3
   その他the organic phase is separated off
4. 4
   乾燥dried over K2CO3
5. 5
   濃縮concentrated
6. 6
   workup.DISTILLATIONthe residue is distilled

実験手順

131 g (0.686 mol) of N-(1,1-dimethoxyprop-2-yl)urethane are added dropwise to 25 g of sodium hydride (80% strength) in 700 ml of absolute toluene at 90° C. When the evolution of hydrogen has ended, 61.2 g (0.8 mol) of allyl chloride are added dropwise at 90° C and the mixture is stirred overnight at 90° C. The sodium chloride which has precipitated out is dissolved with water, the organic phase is separated off, dried over K2CO3 and concentrated and the residue is distilled.

出典