反応 #64315

ord-42668a80998344b19de3080d89fd669a

反応方程式

CC(C)(c1ccccc1)n1nnc(-c2ccccc2)n1
2-(1-methyl-1-phenylethyl)-5-phenyl-2H-tetrazole
COC(=O)c1ccc(Br)cc1
methyl 4-bromobenzoate
COC(=O)c1ccc(-c2ccccc2-c2nnn(C(C)(C)c3ccccc3)n2)cc1
2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

reacting the ortho-transmetalated 2-(1-methyl-1-phenylethyl)-5-phenyl-2H-tetrazole with methyl 4-bromobenzoate in the presence of phosphinated nickel catalyst to give 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester,

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05412102uspto-grants-1995_05