反応 #64242

ord-ecd17fce5fe54de281b5939c329ed015

反応方程式

N#CCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
2-cyano-N-(trans-4-nitroxycyclohexyl)-acetic acid amide
N#CCC(=O)N[C@H]1CC[C@H](O)CC1
2-cyano-N-(trans-4-hydroxycyclohexyl)-acetic acid amide
→
CC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
trans-N-acetyl-4-nitroxycyclohexylamine
収率 53.0%

反応物

N#CCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
2-cyano-N-(trans-4-nitroxycyclohexyl)-acetic acid amide
N#CCC(=O)N[C@H]1CC[C@H](O)CC1
2-cyano-N-(trans-4-hydroxycyclohexyl)-acetic acid amide

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

2-cyano-N-(trans-4-nitroxycyclohexyl)-acetic acid amide from 2-cyano-N-(trans-4-hydroxycyclohexyl)-acetic acid amide melting point: 149°-150° C. (ether), yield: 53% of theory.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05411989uspto-grants-1995_05