反応 #63753

反応方程式

2-[(2-pyridylmethyl)sulphinyl]benzimidazole

n-propyl mercaptan

hydrochloric acid

→

1-(2-benzimidazolyl)-2-[(propyldithio)methyl]pyridinium chloride

溶媒

tetrahydrofuran

反応条件

後処理

1. 1
   その他evaporated in vacuo
2. 2
   その他The residue is crystallized from ethanol/ether

実験手順

2.6 g of 2-[(2-pyridylmethyl)sulphinyl]benzimidazole are dissolved in 30 ml of tetrahydrofuran and treated with 1.0 ml of n-propyl mercaptan. 10 ml of 3N hydrochloric acid are added at an internal temperature of 40°. The mixture is stirred at 40° for 5 minutes and then evaporated in vacuo. The residue is crystallized from ethanol/ether. There is obtained 1-(2-benzimidazolyl)-2-[(propyldithio)methyl]pyridinium chloride of melting point 144°-145°.

出典