反応 #63426

反応方程式

sodium

dimethyl malonate

4-[4'-(2",4"-dichloro-phenoxy)-phenoxy]-2-pentenoyl chloride

→

faint yellow crystalline desired compound

収率 79.5%

dimethyl-4-[4'-(2",4"-dichloro-phenoxy)-phenoxy]-2-pentenoyl-malonate

収率 79.5%

溶媒

ether

ether

反応条件

後処理

1. 1
   workup.ADDITIONis added dropwise
2. 2
   温度The reaction mixture is heated

実験手順

From 4.6 g of sodium, 26 g of dimethyl malonate and 60 ml of ether a dimethyl sodium malonate solution is prepared which is added dropwise under stirring to a mixture of 37 g of 4-[4'-(2",4"-dichloro-phenoxy)-phenoxy]-2-pentenoyl chloride and 50 ml of ether. The reaction mixture is heated to boiling for 2 hours and worked up as described in Example 1. Thus 37 g of the faint yellow crystalline desired compound are obtained, yield 79%, mp.: 60°-63° C.

出典