反応 #632021

反応方程式

4-(5-nitro-pyrimidin-2-yl)-1,4-diaza-bicyclo[3.2.2]nonane

→

2-(1,4-Diaza-bicyclo[3.2.2]non-4-yl)-pyrimidin-5-ylamine

収率 100.0%

溶媒

methanol

反応条件

後処理

1. 1
   ろ過The reaction-mixture was filtered through celite
2. 2
   洗浄was washed with ethanol (50 ml)
3. 3
   その他The product was dried
4. 4
   その他evaporated

実験手順

A mixture of 4-(5-nitro-pyrimidin-2-yl)-1,4-diaza-bicyclo[3.2.2]nonane (0.71 g, 2.85 mmol), palladium (0.25 g, 10% on activated carbon) and methanol (50 ml) was stirred under hydrogen for 10 min. The reaction-mixture was filtered through celite and was washed with ethanol (50 ml). The product was dried and evaporated. Yield 100%.

出典