反応 #631993

反応方程式

Ethyl vinyl ether

6-carbomethoxy-4,4-dimethylcyclohexan-1-ol

→

2-carbomethoxy-4,4-dimethyl-1-(2-methyl-1,3-dioxapent-1-yl)cyclohexane

収率 98.0%

溶媒

Et2O

反応条件

後処理

1. 1
   洗浄After 30 minutes the mixture was washed with saturated aqueous NaHCO3
2. 2
   workup.DISTILLATIONAfter distillation (Bp 110-120° C./10 torr)

実験手順

Ethyl vinyl ether (10.5 g) were added slowly and dropwise to 50 ml of Et2O containing 6-carbomethoxy-4,4-dimethylcyclohexan-1-ol (25 g) at 0° C. under nitrogen. After 30 minutes the mixture was washed with saturated aqueous NaHCO3. After distillation (Bp 110-120° C./10 torr) were obtained 34 g of 2-carbomethoxy-4,4-dimethyl-1-(2-methyl-1,3-dioxapent-1-yl)cyclohexane (yield 98%)

出典