反応 #6299

反応方程式

4-triflyltoluene

N-bromosuccinimide

benzoyl peroxide

→

4-Triflyl-alpha-bromotoluene

溶媒

carbon tetrachloride

carbon tetrachloride

反応条件

後処理

1. 1
   温度at reflux for 20 hours
2. 2
   その他the solid byproducts are removed by filtration
3. 3
   濃縮The filtrate is concentrated in vacuo
4. 4
   その他the product is purified by recrystallization from benzene

実験手順

A stirred solution of 22.4 g (0.1 mole) of 4-triflyltoluene, 178 g (0.1 mole) of N-bromosuccinimide, and 0.48 g (0.2 mole %) of benzoyl peroxide in carbon tetrachloride is heated at reflux for 20 hours. After cooling to room temperature, the reaction is diluted by the addition of carbon tetrachloride, and the solid byproducts are removed by filtration. The filtrate is concentrated in vacuo, and the product is purified by recrystallization from benzene.

出典