反応 #6297

反応方程式

4-(N-4-hydroxybutyl-N-butylamino)benzaldehyde

acetic anhydride

triethylamine

→

4-(N-4-acetoxybutyl-N-butylamino)benzaldehyde

溶媒

dichloromethane

反応条件

後処理

1. 1
   洗浄The product solution is washed with cold 2N HCl
2. 2
   ろ過with filtered through cotton
3. 3
   その他evaporated to dryness

実験手順

To a stirred solution of 249.4 g (1 mole) of 4-(N-4-hydroxybutyl-N-butylamino)benzaldehyde in dichloromethane are added 153.1 g (1.5 moles) of acetic anhydride, 151.8 g (1.5 moles) of triethylamine, and 8.5 g (7 mole %) of 4-N,N-dimethylaminopyridine. The reaction mixture is stirred at room temperature for 16 hours. The product solution is washed with cold 2N HCl and then with filtered through cotton, and evaporated to dryness.

出典