反応 #6266

反応方程式

rhodanine

benzaldehyde

piperidine

→

desired compound

収率 66.6%

5-benzylidenerhodanine

収率 66.6%

溶媒

ethanol

反応条件

後処理

1. 1
   温度the mixture was heated
2. 2
   温度under reflux for 5 hours
3. 3
   温度After cooling
4. 4
   ろ過the precipitated crystals were filtered
5. 5
   洗浄washed with cooled ethanol

実験手順

To a solution of 10 g (75.1 mmol) of rhodanine and 7.63 ml (75.1 mmol) of benzaldehyde in 150 ml of ethanol, 0.74 ml (7.5 mmol) of piperidine was added, and the mixture was heated under reflux for 5 hours. After cooling, the precipitated crystals were filtered and washed with cooled ethanol to give 11.07 g of the desired compound (66.6% yield, pale yellow crystals).

出典