反応 #62088

反応方程式

[6-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthren-2-yloxy]-acetic acid methyl ester

sodium hydroxide

→

title compound

収率 100.0%

[6-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthren-2-yloxy]-acetic acid sodium salt

収率 100.0%

溶媒

methanol

反応条件

後処理

1. 1
   濃縮After this time, the mixture was concentrated in vacuo to dryness

実験手順

To a solution of [6-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthren-2-yloxy]-acetic acid methyl ester (22 mg, 0.045 mmol in methanol (2 ml) was added solid sodium hydroxide (2 mg, 0.045 mmol). The mixture was stirred vigorously and heated to 60° C. for 1 hour. After this time, the mixture was concentrated in vacuo to dryness to give the title compound (22.4 mg, 100%) and used without any further purification.

出典