反応 #61972

反応方程式

4-hydroxybenzaldehyde

1-bromo-3-chloropropane

potassium carbonate

→

title compound

4-(3-Chloro-propoxy)-benzaldehyde

溶媒

acetone

反応条件

後処理

1. 1
   温度was heated
2. 2
   温度to reflux for 16 h
3. 3
   ろ過The resulting mixture was filtered
4. 4
   その他the filtrate was evaporated
5. 5
   workup.DISTILLATIONDistillation of the residue (0.5 mm Hg, 220° C.)

実験手順

A suspension of 4-hydroxybenzaldehyde (40 g), 1-bromo-3-chloropropane (63 mL), and potassium carbonate (136 g) in acetone (920 mL) was heated to reflux for 16 h. The resulting mixture was filtered, and the filtrate was evaporated. Distillation of the residue (0.5 mm Hg, 220° C.) gave the title compound as a pale yellow oil that crystallized on standing (46 g).

出典