反応 #61970

反応方程式

4-iodophenol

1-bromo-3-chloropropane

potassium carbonate

→

title compound

1-(3-Chloro-propoxy)-4-iodo-benzene

溶媒

acetone

反応条件

後処理

1. 1
   温度was heated
2. 2
   温度at reflux for 16 h
3. 3
   ろ過The suspension was filtered
4. 4
   その他the filtrate was evaporated in vacuo
5. 5
   workup.DISTILLATIONKugelrohr distillation of the residue (5-10 mm Hg, 210° C.)

実験手順

A suspension of 4-iodophenol (20 g), 1-bromo-3-chloropropane (18 mL), and potassium carbonate (38 g) in acetone (250 mL) was heated at reflux for 16 h and allowed to cool to room temperature. The suspension was filtered, and the filtrate was evaporated in vacuo. Kugelrohr distillation of the residue (5-10 mm Hg, 210° C.) gave the title compound as a white crystalline solid (22 g).

出典