反応 #619129

ord-83870ae0c8894d7b988af48427965aa0

反応方程式

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
OC[C@@H](S)[C@@H](S)CO
dithio-erythritol
ClCCN1CCOCC1
N-(2-chloroethyl)-morpholine
→
O=C(Nc1ncc(SCCN2CCOCC2)s1)N(C1CCCCC1)C1CCCCC1
1,1-Dicyclohexyl-3-[5-(2-morpholin-4-yl-ethylsulfanyl)-thiazol-2-yl]-urea

反応物

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
OC[C@@H](S)[C@@H](S)CO
dithio-erythritol
ClCCN1CCOCC1
N-(2-chloroethyl)-morpholine

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他Prepared

実験手順

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithio-erythritol and N-(2-chloroethyl)-morpholine

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: USRE045183E1uspto-grants-2014_10