反応 #61724

反応方程式

(2E)-3-(dimethylamino)-1-(4-chlorophenyl)prop-2-en-1-one

4-(amidinoamino)benzamide nitrate

potassium carbonate

→

title compound

4-{(4-(4-Chlorophenyl)pyridin-2-yl)amino}benzamide

溶媒

ethanol

反応条件

後処理

1. 1
   その他the resulting solid was collected
2. 2
   洗浄then washed with ethanol, water, and diethyl ether

実験手順

To a solution of (2E)-3-(dimethylamino)-1-(4-chlorophenyl)prop-2-en-1-one (0.10 g, 0.48 mmol), 4-(amidinoamino)benzamide nitrate (0.116 g, 0.48 mmol), and potassium carbonate (0.132 g, 0.96 mmol) in ethanol (10 ml) with was heated to 120° C. overnight in a sealed vessel. The reaction mixture was cooled to room temperature and the resulting solid was collected then washed with ethanol, water, and diethyl ether to provide the title compound as a beige solid, identical in all respects with the compound prepared in Example 1.

出典