反応 #6155

反応方程式

tetrahydro-3-hexyl-4-oxo-(R)-6-undecyl-2H-pyran-2-one

→

(3S,4S,6R)-tetrahydro-3-hexyl-4-hydroxy-6-undecyl-2H-pyran-2-one

溶媒

ethyl acetate

反応条件

後処理

1. 1
   ろ過The catalyst was filtered off
2. 2
   その他the solution was evaporated
3. 3
   その他After recrystallization

実験手順

M)c) 8 g of an isomer mixture of tetrahydro-3-hexyl-4-oxo-(R)-6-undecyl-2H-pyran-2-one were dissolved in 2 l of ethyl acetate and 3 g of PtO2 were added. The mixture was then hydrogenated (50 bar) for 12 hours. The catalyst was filtered off and the solution was evaporated. After recrystallization there were obtained 7 g of (3S,4S,6R)-tetrahydro-3-hexyl-4-hydroxy-6-undecyl-2H-pyran-2-one, m.p. 108°-109° C.

出典