反応 #61467

反応方程式

6-chloro-2-piperazin-1-yl-quinoline hydrochloride

2-morpholin-4-yl-5-nitro-benzoic acid

ethyl acetate

→

title compound

[4-(6-Chloro-quinolin-2-yl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl) -methanone

溶媒

acetonitrile

反応条件

実験手順

Prepared in analogy to example 1.1 b) from 6-chloro-2-piperazin-1-yl-quinoline hydrochloride (Example 1.20b) and 2-morpholin-4-yl-5-nitro-benzoic acid (Example 2.1) in acetonitrile. Chromatography (SiO2; ethyl acetate) yields the title compound as a colorless solid. MS (m/e): 482.2 (M+H+; 100%)

出典