反応 #61173

反応方程式

dimethyl-(4-nitro-3-piperidin-1-yl-phenyl)-amine

MeOH

→

title compound

収率 100.0%

4-N,N-Dimethyl-2-piperidin-1-yl-benzene-1,4-diamine

収率 100.0%

反応条件

後処理

1. 1
   その他as prepared in the previous step)

実験手順

Using a procedure similar to Example 3, step (c), dimethyl-(4-nitro-3-piperidin-1-yl-phenyl)-amine (100 mg, 0.4 mmol, as prepared in the previous step) was stirred with 80 mg 5% Pd—C in 5 mL MeOH under H2 to afford 89 mg (100%) of the title compound as an oil, which was used immediately without further purification. Mass spectrum (ESI, m/z) calcd. for C13H21N3, 220.1 (M+H), found 220.1.

出典