反応 #610220

反応方程式

3,3″-bis(phenyl)-9′-[(phenyl)sulfonyl]-9,3′:6′,9″-ter-9H-carbazole

potassium hydroxide

HCl

→

3,3″-Bis(phenyl)-9,3′:6′,9″-ter-9H-carbazole

溶媒

dimethyl sulfoxide

water

反応条件

後処理

1. 1
   温度under reflux for 1 h
2. 2
   抽出The mixture is then extracted with dichloromethane
3. 3
   その他The solvent is evaporated in vacuo
4. 4
   その他the residue is purified by chromatography (heptane/ethyl acetate 10:1)

実験手順

97 g (123 mmol) of 3,3″-bis(phenyl)-9′-[(phenyl)sulfonyl]-9,3′:6′,9″-ter-9H-carbazole and 48 g (856 mmol) of potassium hydroxide in 65 ml of dimethyl sulfoxide and 21 ml of water are heated under reflux for 1 h. The mixture is subsequently cooled to room temperature and neutralised using 1 M HCl solution. The mixture is then extracted with dichloromethane. The solvent is evaporated in vacuo, and the residue is purified by chromatography (heptane/ethyl acetate 10:1). Yield: 64.8 g (100 mmol), 80%.

出典