反応 #60810
ord-bfa91bba01444c858e262522dcf3c6d5
反応方程式
sodium thiomethoxide
6-methyl-4-chlorothieno[3,2-d]pyrimidine
→
title compound
収率 97.0%
6-Methyl-4-(methylthio)thieno[3,2-d]pyrimidine
収率 97.0%
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1ろ過The mixture was filtered
- 2洗浄the solid was washed with acetonitrile
- 3その他The combined filtrate and washes were evaporated
実験手順
A solution of sodium thiomethoxide (24S mg) and 6-methyl-4-chlorothieno[3,2-d]pyrimidine (Acta Pol. Pharm. (1986), 43(2), 97-100) (650 mg) in acetonitrile (50 mL) was stirred overnight. The mixture was filtered and the solid was washed with acetonitrile. The combined filtrate and washes were evaporated to give the title compound as a white solid (665 mg, 97%);