反応 #607718

反応方程式

1,1-dimethylethyl 6-oxa-9-azaspiro[4.5]decane-9-carboxylate

trifluoroacetic acid

→

title compound

収率 173.4%

6-Oxa-9-azaspiro[4.5]decane

収率 173.4%

溶媒

DCM

反応条件

後処理

1. 1
   その他The solvent was evaporated

実験手順

To a of solution 1,1-dimethylethyl 6-oxa-9-azaspiro[4.5]decane-9-carboxylate (200 mg, 0.829 mmol, available from Tyger Scientific Inc) in DCM (3 ml) was added trifluoroacetic acid (TFA) (0.5 ml). The resulting colourless yellow solution was stirred at room temperature for 24 hr. The solvent was evaporated to give the title compound as a grey oil (203 mg).

出典