反応 #60770

反応方程式

isocyanate

4-amino-3-(4-(methylamino)phenyl)-thieno[2,3-d]pyrimidine

2-fluoro-5-trifluoromethyl-phenyl isocyanate

→

4-Amino-3-(4-((2-fluoro-5-(trifluoromethyl)phenyl)-aminocarbonyl(N-methylamino))phenyl)thieno[2,3-d]pyrimidine

反応条件

後処理

1. 1
   その他The compound was prepared

実験手順

The compound was prepared following the procedure described in Example 429, substituting 4-amino-3-(4-(methylamino)phenyl)-thieno[2,3-d]pyrimidine as the amine and using 2-fluoro-5-trifluoromethyl-phenyl isocyanate as the isocyanate of choice. MH+=462.

出典