反応 #607465

ord-8de20b3680e8494681f8a5b2e1a10932

反応方程式

O=c1c2ccccc2ncn1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1
1c
O=c1c2ccccc2ncn1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1
3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl) quinazoline-4 (3H)-one
COc1ccccc1N1CCNCC1
1-(2-methoxyphenyl)piperazine
COc1ccccc1N1CCN(CCn2cnc3ccccc3c2=O)CC1
3-(2-(4-(2-methoxyphenyl)piperazine-1-yl)ethyl)quinazoline-4 (3H)-one

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他This compound was prepared in compliance with the procedure

実験手順

This compound was prepared in compliance with the procedure described in 1c, using 1-(2-methoxyphenyl)piperazine instead of 1-(3-(trifluoromethyl)phenyl)piperazine.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US09326984B2uspto-grants-2016_05