反応 #60574

ord-330a54dcbc11486699277462ebd22a21

反応方程式

C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
compound ( i )
C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
Asn-Leu vinylsulfone
NC(=O)C[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O
Glu asparagine
→
C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)O
Glu-Asn-Leu vinylsulfone

反応物

C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
compound ( i )
C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
Asn-Leu vinylsulfone
NC(=O)C[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O
Glu asparagine

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他This compound is synthesized

実験手順

This compound is synthesized as described above for compound (i), except that Glu-asparagine is used in step (g).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07427591B2uspto-grants-2008_09