反応 #60414

反応方程式

1-[2-(4,4-dimethylcyclohex-1-enyl)-5-methoxyphenyl]-4-pentylpiperazine hydrochloride

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title compound

収率 38.4%

1-[2-(4,4-Dimethylcyclohexyl)-5-methoxyphenyl]-4-pentylpiperazine hydrochloride

収率 38.4%

溶媒

methanol

反応条件

後処理

1. 1
   濃縮the filtrate was concentrated under reduced pressure
2. 2
   workup.ADDITIONDiethyl ether was added to the residue
3. 3
   ろ過the mixture was filtered

実験手順

To a solution of 1-[2-(4,4-dimethylcyclohex-1-enyl)-5-methoxyphenyl]-4-pentylpiperazine hydrochloride (44 mg) prepared in Example (1f) in methanol (5 mL) was added 10% palladium on carbon (100 mg, wet), and the mixture was stirred for 17 hours under a hydrogen atmosphere at atmospheric pressure and room temperature. The reaction mixture was passed through Celite, and the filtrate was concentrated under reduced pressure. Diethyl ether was added to the residue and the mixture was filtered to give 17 mg of the title compound as a light yellow solid.

出典