反応 #60068

反応方程式

2-[2-(2,4-dichlorophenyl)-2-oxoethyl]isoindoline-1,3-dione

→

2-{2-(2,4-dichlorophenyl)-1-[(dimethylamino)methylene]-2-oxoethyl}isoindoline-1,3-dione

溶媒

N,N-dimethylformamidedimethyl acetal

反応条件

後処理

1. 1
   濃縮The reaction mixture was concentrated in vacuo
2. 2
   その他purified by trituration with diethyl ether

実験手順

1 mmol of 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]isoindoline-1,3-dione was heated to 80° C. in N,N-dimethylformamidedimethyl acetal for six hours. The reaction mixture was concentrated in vacuo and purified by trituration with diethyl ether to obtain 2-{2-(2,4-dichlorophenyl)-1-[(dimethylamino)methylene]-2-oxoethyl}isoindoline-1,3-dione.

出典