反応 #59929

反応方程式

( 24f )

2-(((3-methyl-4-((1-methyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

(1-cyclopropyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methanol

→

title compound

収率 3.2%

2-(((4-((1-cyclopropyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

収率 3.2%

反応条件

後処理

1. 1
   その他obtained in the step (37c) above

実験手順

The same procedure as in the steps (24b) to (24f) of Example 24 was repeated using (1-cyclopropyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methanol obtained in the step (37c) above to obtain the title compound (147 mg, total yield: 3.2%) as a light yellow solid.

出典