反応 #59914

反応方程式

( 6f )

2-(((4-((2-methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

1,4-dioxaspiro[4.5]decan-8-ol

→

title compound

収率 7.3%

2-(((4-(1,4-dioxaspiro[4.5]dec-8-yloxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

収率 7.3%

反応条件

後処理

1. 1
   その他obtained in the step (27a)

実験手順

The same procedure as in the steps (6b) to (6f) of Example 6 was repeated using 1,4-dioxaspiro[4.5]decan-8-ol obtained in the step (27a) to obtain the title compound (230 mg, total yield: 7.3%) as a light yellow solid.

出典