反応 #59913

反応方程式

6e

2-(((4-((2-methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole

( 6f )

2-(((4-((2-methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

2,2-dimethyl-1,3-dioxan-5-ol

→

title compound

収率 18.0%

2-(((4-((2,2-dimethyl-1,3-dioxan-5-yl)oxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

収率 18.0%

反応条件

後処理

1. 1
   その他obtained in the step (9a)

実験手順

The same procedure as in the steps (6d), (6e), and (6f) of Example 6 was repeated using 2,2-dimethyl-1,3-dioxan-5-ol obtained in the step (9a) to obtain the title compound (530 mg, total yield: 18%) as a light yellow solid.

出典