反応 #59906

反応方程式

( 21b )

2-(((4-(6,10-dioxaspiro[4.5]dec-8-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

2-(hydroxymethyl)-1,3-propanediol

cyclobutanone

→

title compound

収率 6.2%

2-(((4-(5,9-dioxaspiro[3.5]non-7-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

収率 6.2%

反応条件

実験手順

The same procedure as in the steps (21a) and (21b) of Example 21 was repeated using 2-(hydroxymethyl)-1,3-propanediol and cyclobutanone to obtain the title compound (265 mg, total yield: 6.2%) as a light yellow solid.

出典