反応 #5973

反応方程式

2-methoxy-4-amino-5-chlorobenzoic acid

HCl

methanol

→

methyl 2-methoxy-4-amino-5-chlorobenzoate

反応条件

後処理

1. 1
   workup.DISSOLUTIONdissolves
2. 2
   その他the solvent removed
3. 3
   workup.ADDITIONether added
4. 4
   ろ過filtered
5. 5
   乾燥dried over magnesium sulfate
6. 6
   その他evaporated to dryness

実験手順

To a solution of 50g of 2-methoxy-4-amino-5-chlorobenzoic acid in 500 ml of methanol is added HCl gas until all the material dissolves. Stirring is continued overnight, the solvent removed, ether added, filtered, dried over magnesium sulfate and evaporated to dryness to obtain methyl 2-methoxy-4-amino-5-chlorobenzoate which is used directly in the next step.

出典