反応 #59018

反応方程式

methyl 4-benzyloxy-2-methoxybenzoate

tetrahydrofuran

→

title compound

収率 98.0%

Methyl 4-hydroxy-2-methoxybenzoate

収率 98.0%

溶媒

methanol

反応条件

後処理

1. 1
   その他The catalyst was removed by filtration
2. 2
   濃縮the filtrate was concentrated in vacuo

実験手順

To a solution of methyl 4-benzyloxy-2-methoxybenzoate (3.08 g) in methanol (5 mL)/tetrahydrofuran (7.5 mL) was added 10% palladium-carbon (0.3 g) at room temperature under an atmosphere of argon, and the mixture was stirred at that temperature for 2 hrs under an atmosphere of hydrogen. The catalyst was removed by filtration, and the filtrate was concentrated in vacuo to afford the title compound (2.02 g).

出典