反応 #5853

反応方程式

N,N'-bis-(2,6-diisopropylphenyl) guanidine

α,α-dichloro-m-xylene

potassium carbonate

→

white powder

収率 32.8%

N,N'-bis-(2,6-diisopropylphenyl)-N"-(3-chloromethylphenyl) methylguanidine

収率 32.8%

溶媒

xylene

反応条件

後処理

1. 1
   温度The thus-formed mixture was then refluxed
2. 2
   温度under heating for 10 hours
3. 3
   温度to cool
4. 4
   その他the insoluble substance was removed by filtration
5. 5
   洗浄The thus-obtained filtrate was washed with water
6. 6
   濃縮concentrated for the purpose
7. 7
   その他of recovering the solvent and unreacted raw materials
8. 8
   その他to obtain a slightly yellow crystal
9. 9
   その他The crystal was then recrystallized from acetone

実験手順

11.4 g (0.03 mole) of N,N'-bis-(2,6-diisopropylphenyl) guanidine, 5.7 g (0.033 mole) of α,α-dichloro-m-xylene and 2.1 g (0.015 mole) of anhydrous potassium carbonate were added to 50 ml of xylene. The thus-formed mixture was then refluxed under heating for 10 hours. After the mixture had been allowed to cool, the insoluble substance was removed by filtration. The thus-obtained filtrate was washed with water and then concentrated for the purpose of recovering the solvent and unreacted raw materials to obtain a slightly yellow crystal. The crystal was then recrystallized from acetone to obtain 5.1 g of white powder.

出典