反応 #58469

反応方程式

(S)-2-carboxymethyl-pyrrolidine-1-carboxylic acid benzyl ester

2-bromoacetophenone

→

title compound

収率 48.3%

(S)-2-(2-Oxo-2-phenyl-ethoxycarbonylmethyl)-pyrrolidine-1-carboxylic acid benzyl ester

収率 48.3%

反応条件

実験手順

The title compound (0.700 g) was prepared from (S)-2-carboxymethyl-pyrrolidine-1-carboxylic acid benzyl ester (1.00 g, Aoyama et al, Chem. Pharm. Bull., 3249, 29,11,1981) and 2-bromoacetophenone (0.760 g) according to the method of description 36.

出典