反応 #58457

ord-df7d5b74ebb24e72a670ebe62c3c5b72

反応方程式

O=C(CBr)c1ccccc1
2-bromoacetophenone
O=C(O)CC1CCCCN1C(=O)OCc1ccccc1
2-carboxymethyl-piperidine-1-carboxylic acid benzyl ester
→
O=C(CC1CCCCN1C(=O)OCc1ccccc1)OCC(=O)c1ccccc1
title compound
O=C(CC1CCCCN1C(=O)OCc1ccccc1)OCC(=O)c1ccccc1
(RS)-2-(2-Oxo-2-phenyl-ethoxycarbonylmethyl)piperidine-1-carboxylic acid benzyl ester

反応物

O=C(CBr)c1ccccc1
2-bromoacetophenone
O=C(O)CC1CCCCN1C(=O)OCc1ccccc1
2-carboxymethyl-piperidine-1-carboxylic acid benzyl ester

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

The title compound (4.0 g) was prepared from 2-bromoacetophenone (2.20 g) and 2-carboxymethyl-piperidine-1-carboxylic acid benzyl ester according to the method of description 36

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07423052B2uspto-grants-2008_09