反応 #583965

反応方程式

3-Methoxypiperonal

nitromethane

ammonium acetate

→

yellow solid

4-Methoxy-6-(2-nitrovinyl)-1,3-benzodioxole

溶媒

acetic acid

反応条件

後処理

1. 1
   その他Solvents are removed in vacuo
2. 2
   ろ過The solution is filtered
3. 3
   洗浄the filtrate is washed with water

実験手順

3-Methoxypiperonal (50.0 g) is combined with 71.9 mL of nitromethane in 250 mL of acetic acid; 36 g of ammonium acetate is added, and the mixture is heated to 50° C. for 4 hrs. Solvents are removed in vacuo; the residue is taken up in water and stirred for 20 min. The solution is filtered; the filtrate is washed with water, then ether, to give 51.8 g of a yellow solid.

出典