反応 #582510

反応方程式

sodium hydroxide

ammonium chloride

pentafluorobenzenesulfonyl chloride

→

pentafluorobenzenesulfonamide

溶媒

acetone

反応条件

後処理

1. 1
   workup.ADDITIONDuring addition, pH
2. 2
   ろ過Precipitated product was filtered
3. 3
   その他recrystallized from toluene

実験手順

To an aqueous solution of ammonium chloride was added dropwise an acetone solution of pentafluorobenzenesulfonyl chloride at room temperature. During addition, pH was adjusted to 7 by an aqueous sodium hydroxide solution. Precipitated product was filtered and recrystallized from toluene to give pentafluorobenzenesulfonamide. The structure was confirmed by 1H-NMR, 19F-NMR and IR.

出典