反応 #582503

反応方程式

Cyclohexanone

sodium hydroxide

4-Hexyloxybenzaldehyde

→

2,6-Bis-(4-hexyloxy-benzylidene)-cyclohexanone

溶媒

ethanol

ethanol

ethanol

water

反応条件

後処理

1. 1
   workup.ADDITIONwas added
2. 2
   workup.STIRRINGthe mixture was stirred at room temperature for 16 h
3. 3
   その他A yellow crystalline solid was isolated by vacuum filtration
4. 4
   洗浄was washed with cold ethanol
5. 5
   その他dried in a vacuum oven

実験手順

Cyclohexanone (2.6 ml, 0.025 mol) was dissolved in ethanol (5 ml), and was added to sodium hydroxide (0.38 g, 0.01 mol) dissolved in water (6 ml) and ethanol (2 ml) and was left to stir for 20 min. 4-Hexyloxybenzaldehyde (10 ml, 0.048 mol), dissolved in ethanol (40 ml), was added and the mixture was stirred at room temperature for 16 h. A yellow crystalline solid was isolated by vacuum filtration and was washed with cold ethanol and dried in a vacuum oven. Yield=4.32 g, 36%. 1H NMR and 13C NMR showed expected signals.

出典