反応 #576683

反応方程式

1,8-dichloroanthraquinone

ammonia

→

1,8-dichloroanthracene

反応条件

後処理

1. 1
   温度the mixture was refluxed for 3 hours
2. 2
   その他the solid was separated off via a Büchner funnel
3. 3
   抽出The aqueous phase was extracted three times with 150 ml each time of dichloromethane
4. 4
   抽出the solid was extracted a number of times with dichloromethane
5. 5
   workup.ADDITIONwhile being treated with ultrasound
6. 6
   乾燥The combined organic phases were dried over magnesium sulfate
7. 7
   その他freed of the solvent on a rotary evaporator
8. 8
   温度65 ml of 12M hydrochloric acid and the mixture was refluxed for three hours
9. 9
   その他The solvent was subsequently removed under reduced pressure
10. 10
    洗浄the solution was washed with saturated sodium hydrogen carbonate solution
11. 11
    乾燥dried over magnesium sulfate
12. 12
    その他Removal of the solvent

実験手順

25 g (91 mmol) of 1,8-dichloroanthraquinone and 65 g (1 mol) of Zn dust were suspended in 1 l of a 20% strength by weight aqueous ammonia solution and the mixture was refluxed for 3 hours. After cooling to room temperature, the solid was separated off via a Büchner funnel. The aqueous phase was extracted three times with 150 ml each time of dichloromethane; the solid was extracted a number of times with dichloromethane while being treated with ultrasound. The combined organic phases were dried over magnesium sulfate and freed of the solvent on a rotary evaporator. The solid, whitish yellow residue was suspended in 600 ml of propanol and 65 ml of 12M hydrochloric acid and the mixture was refluxed for three hours. The solvent was subsequently removed under reduced pressure, the residue was taken up in dichloromethane, the solution was washed with saturated sodium hydrogen carbonate solution and dried over magnesium sulfate. Removal of the solvent gave 1,8-dichloroanthracene as a yellow solid which was recrystallized from propanol.

出典