反応 #5749

ord-6cc3dc8dfa924976a59acdde99fd9910

反応方程式

CC1=C(C(=O)[O-])C(c2ccccc2)C(C(=O)OCC=CC(C)(C)C)=C(C)N1
(+) tertbutyl,allyl 2,6-dimethyl-4phenyl-1,4-dihydropyridine-3,5-dicarboxylate
O=C[O-].[NH4+]
ammonium formate
c1ccc(P(c2ccccc2)c2ccccc2)cc1
triphenylphospine
CC1=C(C(=O)O)C(c2ccccc2)C(C(=O)OC(C)(C)C)=C(C)N1
(+)-tertbutyl 2,6-dimethyl-4-phenyl-5-carboxy-1,4-dihydropyridine-3-carboxylate

溶媒

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

A sample of (+) tertbutyl,allyl 2,6-dimethyl-4phenyl-1,4-dihydropyridine-3,5-dicarboxylate is treated in dioxane with 10% Pd on C, ammonium formate and triphenylphospine to give (+)-tertbutyl 2,6-dimethyl-4-phenyl-5-carboxy-1,4-dihydropyridine-3-carboxylate.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05245039uspto-grants-1993_09