反応 #5741

反応方程式

n-dodecyl alcohol

chlorosulfonyl isocyanate

→

white solid

収率 101.6%

Dodecyl(chlorosulfonyl)carbamate

収率 101.6%

溶媒

Et2O

Et2O

反応条件

後処理

1. 1
   濃縮concentrated in vacuo
2. 2
   その他The residue was triturated with cold hexanes
3. 3
   その他to give a white solid
4. 4
   ろ過collected by filtration

実験手順

A solution of n-dodecyl alcohol (10.7 g, 57.4 mmoles) in 100 mL Et2O was added dropwise to a solution of chlorosulfonyl isocyanate (5.0 mL, 57.4 mmoles) in 100 mL Et2O at ~15° C. under an atmosphere of N2. The resulting mixture was stirred for 2 hours and concentrated in vacuo. The residue was triturated with cold hexanes to give a white solid and collected by filtration to give 19.12 g of a white solid, mp 62°-63° C.

出典