反応 #56882

反応方程式

4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine

4-nitro-phenylamine

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title compound

収率 74.0%

6-(5-Bromo-2-methyl-phenyl)-N*4*-(4-nitro-phenyl)-pyrimidine-2,4-diamine

収率 74.0%

反応条件

実験手順

Following the method described in Example 26, 4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine and 4-nitro-phenylamine provided the title compound (74% yield). 1H NMR (CD3OD) δ 2.41 (s, 3H, CH3), 6.42 (s, 1H, Ar), 7.39 (d, 1H, J=8.0 Hz, Ar), 7.67-7.70 (m, 2H, Ar), 8.14 (d, 2H, J=9.0 Hz, Ar), 8.31-8.34 (m, 2H, Ar).

出典