反応 #56838

反応方程式

4-chloro-6-(5-chloro-2-methyl-phenyl)-2-methyl-pyrimidine

4-bromoaniline

→

title compound

収率 21.0%

[6-(5-Chloro-2-methyl-phenyl)-2-methyl-pyrimidin-4-yl]-(4-bromo-phenyl)-amine

収率 21.0%

反応条件

実験手順

Following the method described in Example 38, 4-chloro-6-(5-chloro-2-methyl-phenyl)-2-methyl-pyrimidine and 4-bromoaniline provided the title compound (21% yield). 1H NMR (DMSO-d6) δ 2.48 (s, 3H, CH3), 2.54 (s, 3H, CH3), 6.71 (s, 1H, Ar), 7.36 (d, 1H, J=8.2 Hz, Ar), 7.42 (dd, 1H, J=8.2 Hz, J=2.2 Hz, Ar), 7.47 (d, 1H, J=2.1 Hz, Ar), 7.52 (d, 2H, J=8.8 Hz, Ar), 7.73 (d, 2H, J=8.8 Hz, Ar), 9.72 (s, 1H, NH).

出典