反応 #565310

反応方程式

3,5-Dichloro-4-dodecyloxybenzoic acid

thionyl chloride

→

3.5-Dichloro-4-dodecyloxybenzoyl chloride

溶媒

ethyl acetate

DMF

反応条件

後処理

1. 1
   温度After this period the solution was cooled
2. 2
   濃縮concentrated under reduced pressure and co-evaporated with ethyl acetate (×1)

実験手順

3,5-Dichloro-4-dodecyloxybenzoic acid (200 g, 0.533 mol) was suspended/dissolved in ethyl acetate (1000 mL) with DMF (0.5 mL) and thionyl chloride (194 mL, 2.66 mol). The mixture was then heated to 60° C. for 2.5 hrs. After this period the solution was cooled, concentrated under reduced pressure and co-evaporated with ethyl acetate (×1). The resulting oil was used as such in the next step.

出典