反応 #565294

反応方程式

N-butylaniline

potassium carbonate

2-bromoheptane

DMF

→

N-butyl-N-(1-methylhexyl)aniline

収率 60.0%

溶媒

water

反応条件

後処理

1. 1
   抽出extracted with ethyl acetate
2. 2
   洗浄The organic phase was washed with water
3. 3
   乾燥dried (MgSO4)
4. 4
   その他evaporated

実験手順

A mixture of N-butylaniline (7.45 parts) anhydrous potassium carbonate (7.5 parts), 2-bromoheptane (13.5 parts) and DMF (25 parts) was stirred at 130° C. for 86 hours. The reaction mixture was poured into water, saturated with salt and extracted with ethyl acetate. The organic phase was washed with water, dried (MgSO4) and evaporated to leave N-butyl-N-(1-methylhexyl)aniline (11.8 parts, approximately 60% strength). This material had acetic anhydride (10 parts) added to it prior to further use.

出典