反応 #56383

ord-a88205c2903543be866b25bf4d868ba8

反応方程式

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C
beclomethasone dipropionate
ClCCl
methylene chloride
CC(C)=O
acetone
→
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C.CCCCCC
beclomethasone dipropionate n-hexane

反応物

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C
beclomethasone dipropionate
ClCCl
methylene chloride
CC(C)=O
acetone

試薬

なし

溶媒

CCCCCC
n-hexane

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他The beclomethasone dipropionate-n-hexane solvate is prepared
  2. 2
    ろ過The precipitate is filtered
  3. 3
    その他dried

実験手順

The beclomethasone dipropionate-n-hexane solvate is prepared by dissolving the beclomethasone dipropionate in a suitable organic solvent, such as methylene chloride or acetone, and then adding n-hexane to this solution resulting in the formation of a precipitate. The precipitate is filtered and dried to afford the beclomethasone dipropionate-n-hexane solvate.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04225597uspto-grants-1980_09