反応 #56261

ord-eb62d8f6b81d4677ae9c5e38bb79c821

反応方程式

CCNc1nc(Cl)nc(NC(C)C)n1
atrazine
Clc1nc(Cl)nc(Cl)n1
cyanuric chloride
CC(C)N
isopropylamine
[Na+].[OH-]
sodium hydroxide
CC(C)Nc1nc(Cl)nc(Cl)n1
2,4-dichloro-6-isopropylamino-s-triazine

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

In particular the preparation of atrazine is generally carried out by a discontinuous method, by reacting, in a first reaction stage, cyanuric chloride with isopropylamine in the presence of sodium hydroxide to give 2,4-dichloro-6-isopropylamino-s-triazine. This latter is reacted, in a second stage, with ethylamine and with a further quantity of sodium hydroxide with the subsequent formation of the desired product: 2-chloro-4-ethylamino-6-isopropylamino-s-triazine.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04224444uspto-grants-1980_09