反応 #55940

反応方程式

n-hexyl iodide

Ethyl 2-amino-5-ethyl-3-thiophenecarboxylate

N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide

→

title compound

N-n-Hexyl-N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide

反応条件

実験手順

Ethyl 2-amino-5-ethyl-3-thiophenecarboxylate (Chemische Berichte 99, 94 (1966)) was converted into N-(3-carbethoxy-5-ethyl-2-thienyl)-2-methylpropanamide by the method described in Example 41. Alkylation of the unpurified product with n-hexyl iodide as described in Example 43 gave the title compound as a light yellow oil, b.p. 145°-147° C./0.25 mm. NMR showed that the material was the correct product.

出典