反応 #55932

反応方程式

3-aminophenol

p-nitrobenzenesulfonyl chloride

acetic acid

→

product

収率 56.6%

3-[(4-Nitrophenyl)sulfonyl]aminophenol

収率 56.6%

溶媒

pyridine

反応条件

後処理

1. 1
   温度was heated at 80° on a steam bath for 4 hours
2. 2
   workup.ADDITIONThe reaction mixture was poured on ice
3. 3
   ろ過The precipitated product was filtered
4. 4
   その他recrystallized from isopropanol

実験手順

A mixture of 3-aminophenol (33 g, 0.3 mole) and p-nitrobenzenesulfonyl chloride (66 g, 0.3 mole) in pyridine (350 ml) was heated at 80° on a steam bath for 4 hours. The reaction mixture was poured on ice and acidified with acetic acid. The precipitated product was filtered and recrystallized from isopropanol and gave 50 g (49%) of product which was used in Part B.

出典